Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs
Нанокаррьеры: надёжный инструмент доставки противораковых препаратов
2022-07-28
SCID: 54.1/xx9cxsu7
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anticancer drug deliverynanomedicine translationnanoparticle imaging agentspolymeric nanoparticlestargeted nanoparticles
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Abstract (AI)
Nanomedicines have gained popularity due to their potential therapeutic applications, especially cancer treatment. Targeted nanoparticles can deliver drugs directly to cancer cells and enable prolonged drug release, reducing off-target toxicity and increasing therapeutic efficacy. However, translating nanomedicines from preclinical to clinical settings has been difficult. Rapid advancements in nanotechnology promise to enhance cancer therapies. Nanomedicine offers advanced targeting and multifunctionality. Nanoparticles (NPs) have several uses nowadays. They have been studied as drug transporters, tumor gene delivery agents, and imaging contrast agents. Nanomaterials based on organic, inorganic, lipid, or glycan substances and synthetic polymers have been used to enhance cancer therapies. This review focuses on polymeric nanoparticle delivery strategies for anticancer nanomedicines.
Key Findings
1
A variety of nanomaterials—organic, inorganic, lipid, glycan-based, and synthetic polymers—have been employed to enhance cancer treatments.
2
Nanomedicines increase therapeutic efficacy through advanced targeting and multifunctionality compared to conventional delivery.
3
Nanoparticles serve multiple roles: drug carriers, tumor gene delivery agents, and imaging contrast agents in cancer therapy.
4
Targeted nanoparticles can deliver anticancer drugs directly to cancer cells, enabling prolonged drug release and reduced off-target toxicity.
5
This review specifically emphasizes polymeric nanoparticle delivery strategies for anticancer nanomedicines.
6
Translation of nanomedicines from preclinical research to clinical application remains difficult despite promising preclinical potential.
Research Object
Polymeric nanoparticle delivery systems for anticancer nanomedicines
Research Subject
Strategies and performance of polymeric nanoparticles as drug delivery carriers for anticancer therapies, including targeted delivery, prolonged release, reduced off-target toxicity, and multifunctionality
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2022-07-28
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