Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope

Pamela J. Björkman, Florian Klein, Michael S. Seaman, Michel C. Nussenzweig, John R. Mascola, M. Juliana McElrath, Ivelin S. Georgiev, Nicole A. Doria‐Rose, Robert T. Bailer, Henning Gruell, Anthony P. West, Lilian Nogueira, Till Schoofs, Jovana Golijanin, Julie Czartoski, Philipp Schommers, Christopher O. Barnes, Nina Suh-Toma, Franziska Bach, Yu E. Lee

2019-05-21

SCID: 54.1/yhpey3r4

Abstract (AI)

glycan. Effective bNAbs can therefore be raised against HIV-1 Env's silent face, suggesting their potential for HIV-1 prevention, therapy, and vaccine development.

Key Findings

Research Object

Research Subject

Publication Details

DOI

10.1016/j.immuni.2019.04.014

Publication Date

2019-05-21

Journal

Publisher

ISSN

Access Type

Author Information

Authors

Pamela J. Björkman

Florian Klein

Michael S. Seaman

Michel C. Nussenzweig

John R. Mascola

M. Juliana McElrath

Ivelin S. Georgiev

Nicole A. Doria‐Rose

Robert T. Bailer

Henning Gruell

Anthony P. West

Lilian Nogueira

Till Schoofs

Jovana Golijanin

Julie Czartoski

Philipp Schommers

Christopher O. Barnes

Nina Suh-Toma

Franziska Bach

Yu E. Lee

Download PDF