Adipocyte-Derived Exosomal MiR-27a Induces Insulin Resistance in Skeletal Muscle Through Repression of PPARγ

Li Chen, Grant M. Hatch, Yang Yu, Hongwei Du, Shengnan Wei, Linjing Feng, Junnan Li, Yao Fan, Ming Zhang, Fan Yao
2018-01-01

SCID:  54.1/zmeuv3t5
These results identify a novel crosstalk signaling pathway between adipose tissue and skeletal muscle in the development of insulin resistance, and indicate that adipose tissue-derived miR-27a may play a key role in the development of obesity-triggered insulin resistance in skeletal muscle.
Publication Details
Publication Date
2018-01-01
Journal
Publisher
ISSN
Access Type
Author Information
Authors
Li Chen
Grant M. Hatch
Yang Yu
Hongwei Du
Shengnan Wei
Linjing Feng
Junnan Li
Yao Fan
Ming Zhang
Fan Yao
Explore More Research
Use the citation graph to discover related papers and expand your research horizons.
Click any node to explore
Download PDF
100%