Carbon Nanodots-Based Sensors: A Promising Tool for Detecting and Monitoring Toxic Compounds

Hassan El-Ramady, Neama Abdalla, Duyen H. H. Nguyen, Arjun Muthu, Tamer Elsakhawy, Mohamed H. Sheta, József Prokisch
2025-05-11

SCID:  54.1/zpk4fd6b
The increasing prevalence of toxic compounds in food, agriculture, and the environment presents a critical challenge to public health and ecological sustainability. Carbon nanodots (CNDs), with their excellent photoluminescence, biocompatibility, and ease of functionalization, have emerged as highly promising materials for developing advanced sensors that target hazardous substances. This review provides a comprehensive overview of the synthesis, functionalization, and sensing mechanisms of CND-based sensors, highlighting their versatile application in detecting toxic compounds such as heavy metals, pesticides, mycotoxins, and emerging contaminants. The article outlines recent advancements in fluorescence, electrochemical, and colorimetric detection strategies and presents key case studies that illustrate the successful application of CNDs in real-world monitoring scenarios. Furthermore, it addresses the challenges associated with reproducibility, scalability, selectivity, and sensor stability and explores future directions for integrating CNDs with smart and sustainable technologies. This review emphasizes the transformative potential of CNDs in achieving rapid, cost-effective, and environmentally friendly toxin detection solutions across multiple domains.
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2025-05-11
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Hassan El-Ramady
Neama Abdalla
Duyen H. H. Nguyen
Arjun Muthu
Tamer Elsakhawy
Mohamed H. Sheta
József Prokisch
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