Synthesis, ADMT prediction, and <i>in vitro</i> and <i>in silico</i> α-glucosidase inhibition evaluations of new quinoline–quinazolinone–thioacetamides

Shahrzad Javanshir, Mohammad Mahdavi, Mohammad G. Dekamin, Bagher Larijani, Milad Noori, Mohammad Halimi, Minoo Khalili Ghomi, Maryam Mohammadi‐Khanaposhtani, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Ensieh Nasli‐Esfahani, Navid Dastyafteh, Sajedeh Safapoor, Samanesadat Hosseini, Azadeh Fakhrioliaei
2023-01-01
SCID:  54.1/zrhh6snr
Abstract (AI)
In this work, a new series of quinoline–quinazolinone–thioacetamide derivatives 9a–p were designed using a combination of effective pharmacophores of the potent α-glucosidase inhibitors.
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2023-01-01
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Shahrzad Javanshir
Mohammad Mahdavi
Mohammad G. Dekamin
Bagher Larijani
Milad Noori
Mohammad Halimi
Minoo Khalili Ghomi
Maryam Mohammadi‐Khanaposhtani
Somayeh Mojtabavi
Mohammad Ali Faramarzi
Ensieh Nasli‐Esfahani
Navid Dastyafteh
Sajedeh Safapoor
Samanesadat Hosseini
Azadeh Fakhrioliaei
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