Ustekinumab use in lactation: drug pharmacokinetics and normal development in exposed infants

Christina L. Balmer, Philip O. Anderson, Julie Korgaard, Jens Kjeldsen, Signe Wildt, Sunanda Kane, Signe Wildt, Mette Julsgaard
2025-12-27

SCID:  54.1/zsbgtqju
Lay Summary Ustekinumab was excreted into breast milk at very low levels after both subcutaneous and intravenous administration. Infant serum levels declined despite ongoing breastfeeding, and long-term follow-up showed normal development and no adverse events, supporting continued breastfeeding during ustekinumab treatment.
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2025-12-27
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Authors
Christina L. Balmer
Philip O. Anderson
Julie Korgaard
Jens Kjeldsen
Signe Wildt
Sunanda Kane
Signe Wildt
Mette Julsgaard
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