Tackling antimicrobial resistance across sub-Saharan Africa: current challenges and implications for the future

Moyad Shahwan, Ammar Abdulrahman Jairoun, Brian Godman, Adrian Brink, Zikria Saleem, Julius Chacha Mwita, Collins E. Jana, Bernard E. Ebruke, Evelyn Wesangula, Amanj Kurdi, Amos Massele, Margaret Oluka, Francis Kalemeera, Joseph Fadare, Johanna C. Meyer, Patrick Okwen, Abiodun Egwuenu, Oliver Ombeva Malande, Natalie Schellack, Loveline Lum Niba, Adefolarin A. Amu, Joseph Elikem Efui Acolatse, Robert Incoom, Israel Abebrese Sefah, Sylvia Opanga, Ibrahim Chikowe, Felix Khuluza, Dan Kibuule, Olayinka O. Ogunleye, Aubrey Chichonyi Kalungia, Janney Wale, Celda Tiroyakgosi, Joyce Kgatlwane, Racheal Tomilola Oguntade, Mobolaji Eniola Alabi, Nondumiso B. Q. Ncube, Anastasia N Guantai, Francis Kachidza Chiumia, Ester Hango, Otridah Kapona, Trust Zaranyika, Mutsa Bwakura‐Dangarembizi, Tapiwanashe Kujinga
2022-07-23

SCID:  54.1/zwfzj7f9
INTRODUCTION: Antimicrobial resistance (AMR) is a concern as this increases morbidity, mortality, and costs, with sub-Saharan Africa having the highest rates globally. Concerns with rising AMR have resulted in international, Pan-African, and country activities including the development of national action plans (NAPs). However, there is variable implementation across Africa with key challenges persisting. AREAS COVERED: Consequently, there is an urgent need to document current NAP activities and challenges across sub-Saharan Africa to provide future guidance. This builds on a narrative review of the literature. EXPERT OPINION: All surveyed sub-Saharan African countries have developed their NAPs; however, there is variable implementation. Countries including Botswana and Namibia are yet to officially launch their NAPs with Eswatini only recently launching its NAP. Cameroon is further ahead with its NAP than these countries; though there are concerns with implementation. South Africa appears to have made the greatest strides with implementing its NAP including regular monitoring of activities and instigation of antimicrobial stewardship programs. Key challenges remain across Africa. These include available personnel, expertise, capacity, and resources to undertake agreed NAP activities including active surveillance, lack of focal points to drive NAPs, and competing demands and priorities including among donors. These challenges are being addressed, with further co-ordinated efforts needed to reduce AMR.
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2022-07-23
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Moyad Shahwan
Ammar Abdulrahman Jairoun
Brian Godman
Adrian Brink
Zikria Saleem
Julius Chacha Mwita
Collins E. Jana
Bernard E. Ebruke
Evelyn Wesangula
Amanj Kurdi
Amos Massele
Margaret Oluka
Francis Kalemeera
Joseph Fadare
Johanna C. Meyer
Patrick Okwen
Abiodun Egwuenu
Oliver Ombeva Malande
Natalie Schellack
Loveline Lum Niba
Adefolarin A. Amu
Joseph Elikem Efui Acolatse
Robert Incoom
Israel Abebrese Sefah
Sylvia Opanga
Ibrahim Chikowe
Felix Khuluza
Dan Kibuule
Olayinka O. Ogunleye
Aubrey Chichonyi Kalungia
Janney Wale
Celda Tiroyakgosi
Joyce Kgatlwane
Racheal Tomilola Oguntade
Mobolaji Eniola Alabi
Nondumiso B. Q. Ncube
Anastasia N Guantai
Francis Kachidza Chiumia
Ester Hango
Otridah Kapona
Trust Zaranyika
Mutsa Bwakura‐Dangarembizi
Tapiwanashe Kujinga
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