Case Study 3: Fragment Hopping to Design Highly Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors

This chapter contains sections titled: Fragment-Based Drug Design Minimal Pharmacophoric Elements and Fragment Hopping Fragment Hopping to Design Novel Inhibitors for Neuronal Nitric Oxide Synthase Fragment Hopping to Optimize Neuronal Nitric Oxide Synthase Inhibitors Application of Neuronal Nitric Oxide Synthase Inhibitors to the Prevention of Cerebral Palsy