A scoping review of large language models for generative tasks in mental health care

Систематический обзор больших языковых моделей для генеративных задач в сфере охраны психического здоровья
Fenglin Liu, David A. Clifton, John Torous, Yining Hua, Hongbin Na, Zehan Li, Xiao Fang
2025-04-30

clinical effectivenessevaluation methodsgenerative taskslarge language modelsmental health care
Large language models (LLMs) show promise in mental health care for handling human-like conversations, but their effectiveness remains uncertain. This scoping review synthesizes existing research on LLM applications in mental health care, reviews model performance and clinical effectiveness, identifies gaps in current evaluation methods following a structured evaluation framework, and provides recommendations for future development. A systematic search identified 726 unique articles, of which 16 met the inclusion criteria. These studies, encompassing applications such as clinical assistance, counseling, therapy, and emotional support, show initial promises. However, the evaluation methods were often non-standardized, with most studies relying on ad-hoc scales that limit comparability and robustness. A reliance on prompt-tuning proprietary models, such as OpenAI's GPT series, also raises concerns about transparency and reproducibility. As current evidence does not fully support their use as standalone interventions, more rigorous development and evaluation guidelines are needed for safe, effective clinical integration.
1
Current evidence does not support using LLMs as standalone mental health interventions; rigorous development and evaluation guidelines are needed for safe clinical integration.
2
Evaluation methods were frequently non-standardized, with ad-hoc scales limiting comparability and the robustness of reported evidence.
3
Heavy reliance on prompt-tuned proprietary models, including OpenAI’s GPT series, raises concerns about transparency and reproducibility.
4
Included studies covered clinical assistance, counseling, therapy, and emotional support, showing initial promise for generative LLM applications.
5
The scoping review identified 726 unique articles, with only 16 meeting inclusion criteria for LLM applications in mental health care.

large language models used for generative tasks in mental health care

their clinical applications, performance, effectiveness, and evaluation methods for safe integration into mental health care

Publication Details
Publication Date
2025-04-30
Journal
Publisher
ISSN
Cited by
127
Access Type
Author Information
Authors
Fenglin Liu
David A. Clifton
John Torous
Yining Hua
Hongbin Na
Zehan Li
Xiao Fang
Explore further
Open the scid.ai AI chat with a ready-made request: it will find papers on a similar topic and help build a literature review.
Find similar papers in the chat →
Make a presentation
100%