Initial sequencing and analysis of the human genome
Первичное секвенирование и анализ генома человека
Bruce W. Birren, Éric Pelletier, Patrick Wincker, Jean Weissenbach, Richard Durbin, Richard Reinhardt, Sean R. Eddy, Elbert Branscomb, Atsushi Toyoda, Takehiko Itoh, Masahira Hattori, Jan‐Fang Cheng, Raymond M. Wheeler, Peer Bork, Warren Gish, Paul Kitts, Yuri I. Wolf, Eugene V. Koonin, James C. Mullikin, Evan E. Eichler, L. Aravind, Huanming Yang, Carrie Sougnez, Raju Kucherlapati, Richard A. Gibbs, Marco A. Marra, Eric S. Lander, David Haussler, Mark S. Guyer, Robert S. Fulton, Elaine R. Mardis, Stephan Beck, Helmut Blöcker, Michael P. Doyle, Lisa L. Cook, Panos Deloukas, Michael C. Wendl, Feng Chen, Yasushi Totoki, Jill P. Mesirov, George M. Weinstock, Erica Sodergren, Alan Coulson, Lee Rowen, Leroy Hood, Tarjei S. Mikkelsen, Chad Nusbaum, David L. Nelson, Rajinder Kaul, Terrence S. Furey, Aravind Subramanian, Chris P. Ponting, Todd M. Lowe, Ewan Birney, Alex Bateman, Nobuyoshi Shimizu, Andrew J. Mungall, Tim Hubbard, Serafim Batzoglou, Christopher B. Burge, R Myers, Ian Dunham, Wonhee Jang, Henning Hermjakob, Lauren Linton, Michael C. Zody, Jennifer Baldwin, Keri Devon, Ken Dewar, William W. Fitzhugh, Roel Funke, Diane Gage, Katrina L. Harris, Andrew Heaford, John G. Howland, Lisa Kann, Jessica A. Lehoczky, R Paul Levine, Paul McEwan, Kevin McKernan, James C. Meldrim, Cher Miranda, William Morris, Jerome W. Naylor, Christina Raymond, Mark Rosetti, Ralph Santos, Andrew Sheridan, Nicole Stange-Thomann, Nikola M. Stojanović, Dudley Wyman, Jane Rogers, John Sulston, R. Ainscough, David Bentley, John H. Burton, Christopher Clee, Nigel Carter, Rebecca Deadman, Andrew Dunham, Lisa French, Darren Grafham, Simon G. Gregory, Sean Humphray, Adrienne Hunt, Matthew C. Jones, Christine Lloyd, Amanda A. McMurray, Lucy Matthews, Simon Mercer, Sarah Milne, R. W. Plumb, Mark T. Ross, R. Shownkeen, Sarah Sims, R Waterston, Richard K. Wilson, LaDeana W. Hillier, John D. McPherson, Lucinda A. Fulton, Asif Chinwalla, Kymberlie Pepin, Stephanie L. Chissoe, Kim D. Delehaunty, Tracie L. Miner, Andrew Delehaunty, Jason Kramer, D. Johnson, Patrick Minx, Sandra W. Clifton, Trevor Hawkins, Paul Predki, Paul Richardson, Sarah Wenning, Tom Slezak, Norman A. Doggett, Anne S. Olsen, Susan Lucas, Christopher J. Elkin, Edward C. Uberbacher, M.E. Frazier, Donna M. Muzny, Steven E. Scherer, John Bouck, Kim C. Worley, Catherine Rives, James H. Gorrell, Michael L. Metzker, Susan L. Naylor, Yoshiyuki Sakaki, Asao Fujiyama, Tetsushi Yada, Chiharu Kawagoe, Hidemi Watanabe, Todd D. Taylor, Roland Heilig, William Saurin, François Artiguenave, Philippe Brottier, Thomas Brüls, Catherine Robert, André Rosenthal, Matthias Platzer, Gerald Nyakatura, Stefan Taudien, Andreas Rump, Andrew R. Smith, Lynn Doucette‐Stamm, Marc Rubenfield, Keith G. Weinstock, Hong Mei Lee, JoAnn Dubois, Yukun He, Jian Wang, Guyang Matthew Huang, Jun Gu, Anup Madan, Shizen Qin, Ronald Davis, Nancy A. Federspiel, A. Pia Abola, Michael Proctor, Bruce A. Roe, Huaqin Pan, Juliane Ramser, Hans Lehrach, W. Richard McCombie, M. de la Bastide, Neilay Dedhia, Klaus Hornischer, Gabriele Nordsiek, Richa Agarwala, Jeffrey A. Bailey, Daniel G. Brown, Christopher B. Burge, Lorenzo Cerutti, Hsiu-Chuan Chen, Deanna M. Church, Michèle Clamp, Richard R. Copley, Tobias Doerks, James E. Galagan, James Gilbert, Cyrus L. Harmon, Yoshihide Hayashizaki, Karsten Hokamp, L. Steven Johnson, Thomas A. Jones, Simon Kasif, Arek Kaspryzk, Scot Kennedy, W. James Kent, Ian Korf, David Kulp, Doron Lancet, Aoife McLysaght, John V. Moran, Nicola Mulder, Victor J. Pollara, Greg Schuler, Jörg Schultz, Guy Slater, Arian F. A. Smit, Elia Stupka, Joseph Szustakowki, Danielle Thierry‐Mieg, Jean Thierry‐Mieg, Lukas Wagner, John Wallis, Alan J. Williams, Kenneth H. Wolfe, Shiaw-Pyng Yang, Ru-Fang Yeh, Francis S. Collins, Jane L. Peterson, Adam L. Felsenfeld, Kris A. Wetterstrand, Jeremy Schmutz, Mark Dickson, Jonathan Wood, David R. Cox, Maynard V. Olson, Christopher K. Raymond, Kazuhiko Kawasaki, Satoshi Minoshima, Glen A. Evans, Μαρία Αθανασίου, Roger A. Schultz, A.A.N. Patrinos, Michael J. Morgan, Aristides Patrinos, The Wellcome Trust:, Michael J. Morgan, Genoscope and CNRS UMR-8030:, Jun Yu, *Genome Analysis Group (listed in alphabetical order, also includes individuals listed under other headings):, Jane Grimwood, Nigel Carter, Douglas R. Smith, Shinsei Minoshima
The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence.
Key Findings
1
An international collaboration produced a draft sequence of the human genome.
2
Initial analysis of the sequence yielded insights into human development, physiology, medicine, and evolution.
3
The draft human genome sequence was made freely available to the scientific community.
4
The study demonstrates the value of the human genome sequence as a resource for biological and medical research.
Research Object
Draft human genome sequence
Research Subject
the draft sequence and initial analysis of the human genome, including insights into human development, physiology, medicine, and evolution