The Interaction of Person-Affect-Cognition-Execution (I-PACE) model for addictive behaviors: Update, generalization to addictive behaviors beyond internet-use disorders, and specification of the process character of addictive behaviors

Модель взаимодействия личности—аффекта—когниции—исполнения (I-PACE) для аддиктивных поведенческих расстройств: обновление, обобщение сверх расстройств, связанных с использованием интернета, и уточнение процессного характера аддиктивных поведений
Trevor W. Robbins, Astrid Müller, Matthias Brand, Marc N. Potenza, Elisa Wegmann, Rudolf Stark, Klaus Wölfling
2019-06-24

Interaction of Person-Affect-Cognition-Execution (I-PACE) modeladdictive behaviorscue-reactivity/cravingfronto-striatal circuits (ventral striatum, amygdala, dorsolateral prefrontal cortex)inhibitory control
We propose an updated version of the Interaction of Person-Affect-Cognition-Execution (I-PACE) model, which we argue to be valid for several types of addictive behaviors, such as gambling, gaming, buying-shopping, and compulsive sexual behavior disorders. Based on recent empirical findings and theoretical considerations, we argue that addictive behaviors develop as a consequence of the interactions between predisposing variables, affective and cognitive responses to specific stimuli, and executive functions, such as inhibitory control and decision-making. In the process of addictive behaviors, the associations between cue-reactivity/craving and diminished inhibitory control contribute to the development of habitual behaviors. An imbalance between structures of fronto-striatal circuits, particularly between ventral striatum, amygdala, and dorsolateral prefrontal areas, may be particularly relevant to early stages and the dorsal striatum to later stages of addictive processes. The I-PACE model may provide a theoretical foundation for future studies on addictive behaviors and clinical practice. Future studies should investigate common and unique mechanisms involved in addictive, obsessive-compulsive-related, impulse-control, and substance-use disorders.
1
Addictive behaviors develop from interactions among predisposing variables, affective and cognitive responses to specific stimuli, and executive functions like inhibitory control and decision-making.
2
An imbalance in fronto-striatal circuits—particularly between ventral striatum, amygdala, and dorsolateral prefrontal areas—is relevant to early stages of addictive processes, with dorsal striatum implicated in later stages.
3
Associations between cue-reactivity/craving and diminished inhibitory control contribute to the development of habitual addictive behaviors.
4
The I-PACE model offers a theoretical foundation for future research and clinical practice, and future studies should examine shared and distinct mechanisms across addictive, obsessive-compulsive-related, impulse-control, and substance-use disorders.
5
Updated I-PACE model is proposed and argued to be valid across multiple addictive behaviors beyond internet-use disorders, including gambling, gaming, buying-shopping, and compulsive sexual behavior disorders.

Interaction of Person-Affect-Cognition-Execution (I-PACE) model for addictive behaviors

Theoretical specification and generalization of the process character, mechanisms, and neural/psychological interactions (predisposing variables, affective and cognitive responses, executive functions, cue-reactivity/craving, inhibitory control, fronto-striatal circuit imbalance, habit formation) underlying various addictive behaviors

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2019-06-24
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Trevor W. Robbins
Astrid Müller
Matthias Brand
Marc N. Potenza
Elisa Wegmann
Rudolf Stark
Klaus Wölfling
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