The biosynthesis of adenosylcobalamin (vitamin B12)
Биосинтез аденозилкобаламина (витамина B12)
2002-06-17
SCID: 54.1/w6mekymh
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adenosylcobalamincobalamin biosynthesisuroporphyrinogen III transformationvitamin B12
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Abstract (AI)
Vitamin B12, or cobalamin, is one of the most structurally complex small molecules made in Nature. Major progress has been made over the past decade in understanding how this synthesis is accomplished. This review covers some of the most important findings that have been made and provides the reader with a complete description of the transformation of uroporphyrinogen III into adenosylcobalamin (AdoCbl). 183 references are cited.
Key Findings
1
Major progress over the past decade has clarified key steps and mechanisms in cobalamin (vitamin B12) biosynthesis.
2
The paper provides a complete description of the biosynthetic transformation of uroporphyrinogen III into adenosylcobalamin (vitamin B12).
3
The review synthesizes and summarizes the most important findings in the field, drawing on 183 cited references.
Research Object
Biosynthetic pathway transforming uroporphyrinogen III into adenosylcobalamin (AdoCbl)
Research Subject
The enzymatic and mechanistic steps, intermediates, and overall biochemical transformation leading to formation of adenosylcobalamin (vitamin B12) from uroporphyrinogen III
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2002-06-17
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