Impact of Microplastics and Nanoplastics on Human Health

Влияние микропластика и нанопластика на здоровье человека
Maxine Swee-Li Yee, Ling‐Wei Hii, Chin-King Looi, Wei‐Meng Lim, Shew Fung Wong, Yih-Yih Kok, Boon-Keat Tan, Chiew-Yen Wong, Chee‐Onn Leong
2021-02-16

epithelial translocationhuman healthmicroplasticsnanoplasticssystemic exposure
Plastics have enormous impacts to every aspect of daily life including technology, medicine and treatments, and domestic appliances. Most of the used plastics are thrown away by consumers after a single use, which has become a huge environmental problem as they will end up in landfill, oceans and other waterways. These plastics are discarded in vast numbers each day, and the breaking down of the plastics from micro- to nano-sizes has led to worries about how toxic these plastics are to the environment and humans. While, there are several earlier studies reported the effects of micro- and nano-plastics have on the environment, there is scant research into their impact on the human body at subcellular or molecular levels. In particular, the potential of how nano-plastics move through the gut, lungs and skin epithelia in causing systemic exposure has not been examined thoroughly. This review explores thoroughly on how nanoplastics are created, how they behave/breakdown within the environment, levels of toxicity and pollution of these nanoplastics, and the possible health impacts on humans, as well as suggestions for additional research. This paper aims to inspire future studies into core elements of micro- and nano-plastics, the biological reactions caused by their specific and unusual qualities.
1
Plastic waste progressively breaks down into microplastics and nanoplastics, creating widespread environmental contamination and concerns about toxicity to humans.
2
Research on microplastic and nanoplastic effects at subcellular and molecular levels in humans remains limited compared with environmental studies.
3
The paper identifies a need for further research into biological responses to the distinctive properties of microplastics and nanoplastics.
4
The potential transport of nanoplastics across gut, lung, and skin epithelia—and consequent systemic human exposure—has not been thoroughly examined.
5
The review examines nanoplastic formation, environmental behavior and degradation, pollution levels, toxicity, and potential human-health effects.

Microplastics and nanoplastics in environmental and human exposure pathways

Their environmental behavior, toxicity, epithelial transport, systemic exposure, and biological health effects in humans

Publication Details
Publication Date
2021-02-16
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1021
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Authors
Maxine Swee-Li Yee
Ling‐Wei Hii
Chin-King Looi
Wei‐Meng Lim
Shew Fung Wong
Yih-Yih Kok
Boon-Keat Tan
Chiew-Yen Wong
Chee‐Onn Leong
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