Chronic respiratory diseases: a global view
Хронические заболевания органов дыхания: глобальный обзор
2020-06-01
SCID: 54.1/ww727h56
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COPD (chronic obstructive pulmonary disease)Global Burden of Disease (GBD) 2017asthmachronic respiratory diseasesdisability-adjusted life-years (DALYs)
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Abstract (AI)
Chronic respiratory diseases are among the most common non-communicable diseases worldwide, largely due to the ubiquity of noxious environmental, occupational, and behavioural inhalational exposures.1 In addition to chronic obstructive pulmonary disease (COPD) and asthma, chronic respiratory diseases include interstitial lung disease, pulmonary sarcoidosis, and pneumoconioses, such as silicosis and asbestosis. Unfortunately, chronic respiratory diseases have received proportionately less public attention and less research funding than other disease entities such as cardiovascular disease, cancer, stroke, diabetes, and Alzheimer's disease.
Key Findings
1
Age-standardised prevalence (−14.3%), mortality (−42.6%), and DALYs (−38.2%) for chronic respiratory diseases all decreased between 1990 and 2017.
2
COPD (3.9% global prevalence) and asthma (3.6% global prevalence) were the most prevalent chronic respiratory diseases and top causes of related deaths.
3
Chronic respiratory diseases caused 3.9 million deaths in 2017, an 18.0% increase since 1990, and 112.3 million total DALYs (1470 DALYs per 100,000).
4
Major actions recommended: strengthen tobacco and pollution control, improve early diagnosis (spirometry, imaging, case-finding), and increase research funding for detection and novel therapies.
5
Nearly 545 million people worldwide had a chronic respiratory disease in 2017, a 39.8% increase since 1990.
6
Regional heterogeneity exists: high-income regions had highest prevalence, south Asia had highest mortality, and sub-Saharan Africa showed unexpectedly low prevalence and mortality, possibly due to underdiagnosis and younger population structure.
7
Risk-factor patterns vary by region and sex: smoking is the leading risk for men everywhere; for women, leading risks include household air pollution, ambient particulate matter, and smoking depending on region.
Research Object
Chronic respiratory diseases (including COPD, asthma, interstitial lung disease, pulmonary sarcoidosis, and pneumoconioses)
Research Subject
Global prevalence, attributable health burden (incidence, mortality, DALYs), regional and sex-specific heterogeneity of risk factors and trends from 1990 to 2017
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2020-06-01
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